生物毒素与人类疾病实验室 发表论文

近5年内发表SCI收录全文论文(“#”表示为通讯作者)

. Lai R, Liu H, Lee WH, Zhang Y#, An anionic antimicrobial peptide from skin secretions of toad Bombina maxima. Biochem Biophys Res Commun. 2002, 295, 796-799.
. Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y#, Antimicrobial peptides from the skin secretion of Chinese red belly toad Bombina maxima. Peptides 2002, 23, 427-435.
. Lee WH, Li Y, Lai R, Li S, Zhang Y#, Wang W, Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. European Journal of Immunoloy 2005, 35, 1220-1229.
. Zhang YX, Lai R, Lee WH, Zhang Y#, Frog albumin is expressed in skin and characterized as a novel potent trypsin inhibitor. Protein Sci. 2005, 14, 2469-2477.
. Lee WH, Zhang J, Zhang YX, Jin Y, Lai R, Zhang Y#, Maximin 9, a novel free thiol containing antimicrobial peptide with anti-mycoplasma activity from frog Bombina maxima. FEBS Lett. 2005, 579, 4443-4448.
. Lee WH, Du XY, Lu QM, Clemetson KJ, Zhang Y#, Stejnulxin, a novel snake C-type lectin-like protein from Trimeresurus stejnegeri venom is a potent platelet agonist acting specifically via GPVI. Thrombosis and Haemostasis 2003, 90, 662-671.
. Zhang YJ, Wang JH, Lee WH, Wang Q, Liu H, Zheng YT, Zhang Y#, Molecular characterization of Trimeresurus stejnegeri venom L-amino acid oxidase with potential anti-HIV activity. Biochem Biophys Res Commun. 2003, 309, 598-604.
. Wang T, Zhang J, Shen JH, Jin Y, Lee WH, Zhang Y#, Maximins S, a novel group of antimicrobial peptides from toad Bombina maxima. Biochem Biophys Res Commun. 2005, 327, 945-951.
. Zhang J, Zhang Y, Wan SG, Wei SS, Lee WH, Zhang Y#, Bm-TFF2, a trefoil factor protein with platelet activation activity from frog Bombina maxima skin secretions. Biochem Biophys Res Commun. 2005, 330, 1027-1033.
. Lee WH, Liu SB, Shen JH, Jin Y, Zhang Y#, Cloning of bradykinin precursor cDNAs from skin of Bombina maxima reveals novel bombinakinin M antagonists and a bradykinin potential peptide. Regulatory Peptides 2005, 127, 207-215.
. Lai R, Liu H, Lee WH, Zhang Y#, A novel probline rich bombesin-related peptide (PR-bombesin) from Bombina maxima. Peptides 2002, 23, 437-442.
. Lai R, Liu H, Lee WH, Zhang Y#, Identification and cloning of a trypsin inhibitor from skin secretions of Chinese red belly toad Bombina maxima. Comp Biochem Physiol B 2002, 131, 47-53.
. Lai R, Yang DM, Lee WH, Zhang Y#, Biological activities of skin secretions of Salamander Tylototriton verrucosus. J Natural Toxins 2002, 11, 245-250.
. Lai R, Liu H, Lee WH, Zhang Y#, Bombinakinin M gene associated peptide, a novel bioactive peptide from skin secretions of the toad Bombina maxima. Peptides 2003, 24, 199-204.
. Lai R, Liu H, Lee WH, Zhang Y#, Two novel Bv8-like peptides from skin secretions of toad Bombina maxima. Comp Biochem Physiol B 2003, 134, 509-514.
. Lee WH, Zhuang QY, Zhang Y#, Cloning and characterization of a blood coagulation factor IX-binding protein from the venom of Trimeresurus stejnegeri. Toxicon 2003, 41, 765-772.
. Lee WH, Zhang Y#, Molecular cloning and characterization of a platelet glycoprotein Ib-binding protein from the venom of Trimeresurus stejnegeri. Toxicon 2003, 41, 885-892.
. He YY, Lee WH, Zhang Y#, Cloning and purification of a-neurotoxins from Ophiophagus hannah venom. Toxicon 2004, 44, 295-303.
. Tai H, Wei Q, Jin Y, Su M, Song JX, Zhou XD, Ouyang HM, Wang WY, Xiong YL, Zhang Y, TMVA, a snake C-type lectin-like protein from Trimeresurus mucrosquamatus venom, activates platelet via GPIb. Toxicon 2004, 44, 649-656.
. Lee WH, Liu SB, Shen JH, Jin Y, Lai R, Zhang Y#, Identification and molecular cloning of a novel neuromedin U analog from the skin secretions of toad Bombina maxima. Regulatory Peptides 2005, 129, 43-47..
. Zhao Y, Jin Y, Lee WH, Zhang Y#, Isolation and characterization of a 22-kDa protein with trypsin inhibitory activity from toad Bufo andrewsi skin. Toxicon 2005, 46, 277-281.
. Zhao Y, Jin Y, Wang JH, Wang RR, Yang LM, Lee WH, Zheng YT, Zhang Y#, A novel heme-containing protein with anti-HIV-1 activity from skin secretions of Bufo andrewsi. Toxicon 2005, 46, 619-624.
. Shen JH, Liu SB, Zhang YX, Jin Y, Lee WH, Zhang Y#, Cloning of novel bombesin precursor cDNAs from skin of Bombina maxima. Regulatory Peptides 2005, 132, 102-106.
. Zhao Y, Jin Y, Wei SS, Lee WH, Zhang Y#, Purification and characterization of an irreversible serine protease inhibitor from skin secretions of Bufo andrewsi Toxicon 2005, 46, 635-640.
. Zhao Y, Jin Y, Lee WH, Zhang Y#, Isolation and molecular characterization of a novel lysozyme from toad skin secretions. Comp Biochem Physiol C Toxicol Pharmacol. 2006, 142, 46-52.
. Zhang YX, Wang YY, Lee WH, Zheng YT, Zhang Y#, Apoptotic activity of frog Bombina maxima skin albumin. Comp Biochem Physiol B Biochem Mol Biol 2006, 143, 153-159.
. Zhong SR, Jin Y, Wu JB, Chen RQ, Jia YH, Wang WY, Xiong YL, Zhang Y, Characterization and molecular cloning of dabocetin, a potent antiplatelet C-type lectin-like protein from Daboia russellii siamensis venom. Toxicon 2006, 47, 104-112.
. Wan SG, Jin Y, Lee WH, Zhang Y#, A snake venom metalloproteinase that inhibited cell proliferation and induced morphological changes of ECV304 cells. Toxicon 2006, 47, 480-489.
. Wan SG, Jin Y, Lee WH, Zhang Y#, Cloning of two novel P-III class metalloproteinases from Trimeresurus stejnegeri venom gland. Toxicon 2006, 47, 465-472.
. Du XY, Sim DS, Lee WH, Zhang Y#, Blood cells as targets of snake toxins. Blood Cells Mol Dis. 2006, 36, 414-421.
. Guo XX, Zeng L, Lee WH, Zhang Y#, Jin Y, Isolation and cloning of a metalloproteinase from king cobra snake venom. Toxicon 2007; Epub ahead of print.
. Jin Y, Lee WH, Zhang Y#, Molecular cloning of serine proteases from elapid snake venoms. Toxion 2007, Epub ahead of print.