药物发现研究组 发表论文

2007年
. Huoqiang Huang, Xulin Pan, Ninghua Tan*, Guangzhi Zeng, Changjiu Ji. 3D-QSAR study of sulfonamide inhibitors of human carbonic anhydrase II. European Journal of Medicinal Chemistry, 2007, 42(3): 365-372

. Yu-Mei Zhang, Ning-Hua Tan*, Huo-Qiang Huang, Guang-Zhi Zeng. Triterpernoid saponins from Metadina trichotoma. Z. Naturforsch. 2007, 62b: 745-748

. Yu-Mei Zhang, Ning-Hua Tan*, Yang Lu, Ying Chang, Rui-Rui Jia. Chamobtusin A, a novel skeleton diterpenoid alkaloid from Chamaecyparis obtusa cv. tetragon. Organic Letters, 2007, 9(22): 4579-4581

. Ai-qun Jia, Ning-hua Tan, Jun Zhou. Cyclopeptides from Sagina japonica (Caryophyllaceae). Chemistry & Biodiversity, 2007, 4(2): 241-247

. Hong Luo, Yajun Liu, Lin Fang, Xuan Li, Ninghua Tan, Keqin Zhang. Coprinus comatus damages nematode cuticles mechanically with spiny balls and produces potent toxins to immobilize nematodes. Applied and Environmental Microbiology, 2007, 73(12): 3916-3923

. Li Wu, Yang Lu, Qi-Tai Zheng, Ning-Hua Tan, Chao-Ming Li, Jun Zhou. Study on the spatial structure of annomuricatin A, a cyclohexapeptide from the seeds of Annona muricata. Journal of Molecular Structure, 2007, 827(1-3): 145-148

. 刘定梅，张玉梅，谭宁华＊，聂四平，周琳业。绿豆的化学成分研究。天然产物研究与开发，2007，19(增刊): 41-42

. 龚庆芳，张玉梅，谭宁华，陈作红。亚稀褶黑菇的化学成分。天然产物研究与开发，2007，19(3): 436-438

. Chu Hong-biao, Tan Ning-hua*, Xiong Jiang, Zhang Yu-mei, Ji Chang-jiu. Chemical constituents of Pedicularis dolichocymba Hand.-Mazz.. Natural Product Research and Development, 2007, 19(4): 584-587

. 许剑锋，谭宁华。干香柏的化学成分研究。中药材，2007，30(6): 669-671

. 谭宁华。植物环肽。云南民族大学学报（自然科学版），2007，16(4): 281-288

. Hong-Biao Chu, Ning-Hua Tan*, Yu-Mei Zhang.Chemical constituents from Pedicularis rex C. B. Clarke. Z. Naturforsch. 2007, in press

. 张玉梅，谭宁华*。墨西哥落羽杉的化学成分。天然产物研究与开发，2007，待发表

. Hong-Jin Han, Ning-Hua Tan*, Guang-Zhi Zeng, Jun-Ting Fan, Huo-Qiang Huang, Chang-Jiu Ji, Rui-Rui Jia, Qin-Shi Zhao, Ying-Jun Zhang, Xiao-Jiang Hao, Li-Qin Wang. Natural inhibitors of DNA topoisomerase I with cytotoxicities. Chemistry & Biodiversity, 2007, accepted

. Hong-Biao Chu, Ning-Hua Tan*, Yu-Mei Zhang, Guang-Zhi Zeng, Mei-Ju Zhu. Chemical constituents of Pedicularis densispica Franch. Journal of Integrative Plant Biology, 2007, accepted

. Ai-Qun Jia, Ning-Hua Tan, Jun Zhou. Two new cyclopeptides from Arenaria oreophila (Caryophyllaceae). Journal of Asian Natural Products Research, 2007, accepted

. 付朝晖，张玉梅，谭宁华*，褚洪标，嵇长久。云南油杉的化学成分研究。天然产物研究与开发，2007，接受发表

. 熊江，古昆，谭宁华。黑顺片的化学成分。天然产物研究与开发，2007，接受发表

. 唐军，谭宁华*，许文彦，嵇长久，潘蓄林，Conan Wang, Norelle L. Daly, David J. Craik. 植物环蛋白的结构研究。云南植物研究，2007，接受发表

. 谭宁华，嵇长久，曾广智，潘蓄林。植物环肽类化合物。吴立军主编：《实用高级药学丛书》-《实用天然有机产物化学》。人民卫生出版社，北京，2007，1248-1283

. 谭宁华。植物环肽（肽类生物碱）。《天然产物化学》-《生物碱》，2007年，待发表

2006年

. Jia Aiqun, Li Xiang, Tan Ninghua, Liu Xiaozhu, Shen Yuemao, Zhou Jun. Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B. Science in China: Series B Chemistry, 2006, 49(1): 63-66

. Jian-Feng Xu, De-Hua Cao, Ning-Hua Tan*, Zhi-Li Liu, Yu-Mei Zhang, Ya-Bin Yang. New lignan glycosides from Cupressus duclouxiana (Cupressaceae). Journal of Asian Natural Products Research, 2006, 8(1-2): 181-185

. Ning-Hua Tan*, Jun Zhou. Plant cyclopeptides. Chemical Reviews, 2006, 106(3): 840-895

. Xulin Pan, Ninghua Tan*, Guangzhi Zeng, Hongjin Han, Huoqiang Huang. 3D-QSAR and docking studies of aldehyde inhibitors of human cathepsin K. Bioorganic & Medicinal Chemistry, 2006, 14: 2771-2778

. Ai Qun Jia, Ning Hua Tan, Jun Zhou. New minor cyclopeptides from Arenaria oreophila (Caryophyllaceae). Chinese Chemical Letters, 2006, 17(4): 477-480

. Ai-Qun Jia, Ning-Hua Tan, Jun Zhou. Cyclopeptidic Constituents from Arenaria oreophila J. D. Hooker (Caryophyllaceae). Journal of Integrative Plant Biology, 2006, 48(6): 740-744

. Hong-Biao Chu, Ning-Hua Tan*. Iridoid glycosides from Pedicularis dolichocymba Hand.-Mazz.. Journal of Integrative Plant Biology, 2006, 48(10): 1250-1253

. Guang-Zhi Zeng, Xu-Lin Pan, Ning-Hua Tan*, Jiang Xiong, Yu-Mei Zhang. Natural biflavones as novel inhibitors of cathepsin B and K. European Journal of Medicinal Chemistry, 2006, 41(11): 1247-1252

. Guang-Zhi Zeng, Ning-Hua Tan*, Xiao-Jiang Hao, Quan-Zhang Mu, Rong-Tao Li. Natural inhibitors targeting osteoclast-mediated bone resorption. Bioorganic & Medicinal Chemistry Letters, 2006, 16: 6178-6180

. 曾广智，黄火强，谭宁华＊，嵇长久，潘蓄林。碳酸酐酶II及其抑制剂研究进展。云南植物研究，2006，28(5): 543-552

. 杨利荣，熊江，谭宁华＊，褚洪标，徐立，李明扬。三色马先蒿的化学成分研究。云南植物研究，2006，28(5): 553-557

. Zhang Yu-Mei, Tan Ning-Hua*. Two new triterpenes from Metadina trichotoma (Rubiaceae). Acta Botanica Yunnanica, 2006, 28(6): 673-675

. 戴好富，谭宁华，周俊。北五味子中的配糖体成分。中国天然药物，2006，4(1): 49-51

. 许剑峰，谭宁华，张玉梅，杨亚滨，柏吉祥。昆明柏的化学成分研究。中草药，2006, 37(6): 838

2005年
. Yu-Mei Zhang, Ning-Hua Tan*, Ya-Bing Yang, Yang Lu, Peng Cao, Yun-Shan Wu. Norlignans from Sequoia sempervirens. Chemistry & Biodiversity, 2005, 2: 497-505

. Chu Hong-Biao, Tan Ning-Hua*. Iridoid glycosides from Pedicularis dolichocymba. Chinese Journal of Organic Chemistry, 2005, 25 (增刊): 77

. Pan Xu-Lin, Tan Ning-Hua*, Han Hong-Jin. 3D-QSAR Analyses of catecholic flavonoids as telomerase inhibitors. Chinese Journal of Organic Chemistry, 2005, 25 (增刊): 333

. Tan Ning-Hua*, Hao Xiao-Jiang, Zhou Jun. Plant cyclopeptides. Chinese Journal of Organic Chemistry, 2005, 25 (增刊): 380

. 熊江，谭宁华*，古昆。贵州苏铁的化学成分。有机化学，2005，25 (增刊): 461

. 许文彦，谭宁华*，韩洪金。小肽类生物活性分子的非核糖体合成途径研究进展。有机化学，2005，25 (增刊): 473

. Zeng Guang-Zhi, Tan Ning-Hua*. Fluorescent assay of human cathepsin K and its inhibitors from plant resources. Chinese Journal of Organic Chemistry, 2005, 25 (增刊): 524

. Yang Ya-Bin, Yang Xue-Qiong, Ding Zhong-Tao, Tan Ning-Hua. Chemical constituents from Hedyotis diffusa. Chinese Journal of Organic Chemistry, 2005, 25 (增刊): 507

. Xulin Pan, Ninghua Tan*, Guangzhi Zeng, Yumei Zhang, Ruirui Jia. Amentoflavone and its derivatives as novel natural inhibitors of human cathepsin B. Bioorganic & Medicinal Chemistry, 2005, 13: 5819-5825

. Rui Rui Jia, Yu Lin Gou, Lok Sze Ho, Chuen-Pei Ng, Ning Hua Tan, Hsiao Chang Chan. Anti-apoptotic activity of Bak Foong Pills and its ingredients on 6-hydroxydopamine-induced neurotoxicity in PC12 cells. Cell Biology International, 2005, 29: 835-842

. 贾爱群，李湘，谭宁华，刘小烛，沈月毛，周俊。太子参环肽B（Heterophyllin B, HB）的酶环化反应。中国科学B辑化学，2005, 35(6): 455-458

. 戴好富，谭宁华，周俊。北五味子中的一个新单萜苷。高等学校化学学报，2005, 26(9): 1659-1661

. Hao-Fu Dai, Shi-Ming Deng, Ning-Hua Tan, Jun Zhou. A new steroidal glycoside from Ophiopogon japonicus (Thunb.) Ker-Gawl.. Journal of Integrative Plant Biology, 2005, 47(9): 1148-1152

. 张玉梅，谭宁华*，黄火强，贾锐锐，曾广智，嵇长久。墨西哥落羽杉中三个活性双黄酮研究。云南植物研究，2005，27(1): 107-110

. 曾广智，谭宁华*，贾锐锐，潘蓄林。组织蛋白酶及其抑制剂研究进展。云南植物研究，2005，27(4): 337-354

. 戴好富，谭宁华，周俊，易元芬。北五味子挥发性化学成分研究。中草药，2005, 36(9): 1309-1310

. 谭宁华，贾爱群，张玉梅，周俊。近十年植物环肽研究新进展。于德泉和吴毓林主偏：《化学进展丛书》-《天然产物化学进展》分册。化学工业出版社，北京，2005，235-250

. 谭宁华，周俊。石竹科（Caryophyllaceae）。周荣汉和段金廒主编：《植物化学分类学》。上海科学技术出版社，上海，2005，565-582

2004年以前代表性论文
. Tan Ning-Hua, Zhou Jun, Chen Chang-Xiang, Zhao Shou-Xun. Cyclopeptides from the roots of Pseudostellaria heterohylla . Phytochemistry, 1993, 32(5): 1327-1330

. 谭宁华，赵守训，周俊，陈昌祥。九子参甙 A 的结构。化学学报， 1995 ， 53 ： 1024-1033

. Tan Ning-Hua, Zhou Jun, Zhao Shou-Xun. Advances in structural elucidation of glucuronide oleanane-type triterpene carboxylic acid 3,28-O-bisdesmosides (1962-1997). Phytochemistry, 1999, 52(2): 153-192

. Zhou Jun and Tan Ninghua. Application of a new TLC chemical method for detection of cyclopeptides in plants. Chinese Science Bulletin, 2000, 45(20):1825-1831

. 谭宁华 ，周俊。主要中草药活性成分研究二十年，《中国药学年鉴 × 2001 》。北京科学技术出版社，北京， 2002 ， 26-31

. Yu-Mei Zhang, Ning-Hua Tan * , Min He, Yang Lu, Su-Qin Shang, Qi-Tai Zheng. Sequosempervirin A, a novel spirocyclic compound from Sequoia sempervirens . Tetrahedron Letters , 2004, 45: 4319-4321