系统生物学研究中心 代表性文章

[1] Dongfang Liu, Liang Xu, Fan Yang, Dongdong Li, Feili Gong, and Tao Xu. Rapid biog enesis and sensitization of secretory lysosomes in NK cells mediated by target-cell recognition. PNAS, 2005, 1:123-127

[2] WU BL, LI PY, LIU YW et al. and RAO ZH. 3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex. PNAS, 2004, 101:8348-8353

[3] PENG H, BARTLAM MARK, ZENG QH, et al. and RAO ZH. Crystal structure of human pirin - An iron-binding nuclear protein and transcription cofactor. J BIOL CHEM, 2004, 279:1491-1498

[4] SHI N, YE S, BARTLAM M et al. and RAO ZH,YUAN JG. Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain. J BIOL CHEM, 2004, 279:4962-4969

[5] Qun-Fang Wan, Yongming Dong, Hua Yang, Xuelin Lou, Jiuping Ding, Tao Xu. Protein Kinase Activation Increases Insulin Secretion by Sensitizing the Secretory Machinery to Ca2+. Journal of General Physiology, 2004, 124:1-11

[6] ZHANG Y, ZHANG ZH, LING LJ et al. and CHEN RS. Conservation analysis of small RNA genes in Escherichia coli. BIOINFORMATICS, 2004, 20:599-603

[7] DD Li, J Xiong, AL Qu, and T Xu. Three-dimensional tracking of single secretory granules in live PC12 cells. Biophysical Journal, 2004, 87(9):1991-2001

[8] LIU BB, BARTLAM MARK, GAO RJ et al. and RAO ZH. Crystal structure of the hyperthermophilic inorganic pyrophosphatase from the Archaeon Pyrococcus horikoshii. BIOPHYS J, 2004, 86:420-427

[9] CAI CX, CHEN JW and CHEN JW. Overexpression of caveolin-1 induces alteration of multidrug resistance in Hs578T breast adenocarcinoma cells. INT J CANCER, 2004, 111:522-529

[10] LIANG XQ, CAO EH, ZHANG Y et al. and CAO EH. A P53 target gene, PIG11, contributes to chemosensitivity of cells to arsenic trioxide. FEBS LETT, 2004, 569:94-98

[11] LIU HL, ZHOU HN, XING WM et al. and BI RC. 2.6 A resolution crystal structure of the bacterioferritin from Azotobacter vinelandii. FEBS LETT, 2004, 573:93-98

[12] ZHAO YG, XU JX and XU JX. The operation of the alternative electron-leak pathways mediated by cytochrome c in mitochondria. BIOCHEM BIOPH RES CO, 2004, 317:980-987

[13] CAI CX, ZHU H, CHEN JW et al. and CHEN JW. Overexpression of caveolin-1 increases plasma membrane fluidity and reduces P-glycoprotein function in Hs578T/Dox. BIOCHEM BIOPH RES CO, 2004, 320:867-874

[14] YANG J, WANG JH, CHEN LH et al. and JIN Q, CHEN RS. Identification and characterization of simple sequence repeats in the genomes of Shigella species. GENE, 2004, 322:85-92

[15] HE J, KANG HJ, YAN F et al. and CHEN C. The endoplasmic reticulum-related events in S-nitrosoglutathione-induced neurotoxicity in cerebellar granule cells. BRAIN RES, 2004, 1025:25-33

[16] XIA S, XU L, BAI L et al. and XU T. Labeling and dynamic imaging of synaptic vesicle-like microvesicles in PC12 cells using TIRFM. BRAIN RES, 2004, 997:159-164

[17] DENG W, SHI BC, HE XL et al. and CHEN RS. Evolution and migration history of the Chinese population inferred from Chinese Y-chromosome evidence. J HUM GENET, 2004, 49:339-348

[18] HU HY, WANG GG, YANG HT et al. and RAO ZH, JIN C. Crystallization and preliminary crystallographic analysis of a native chitinase from the fungal pathogen Aspergillus fumigatus YJ-407. ACTA CRYSTALLOGR D, 2004, 60:939-940

[19] LIU BB, LI XM, GAO RJ et al. and RAO ZH. Crystallization and preliminary X-ray analysis of inorganic pyrophosphatase from the hyperthermophilic archaeon Pyrococcus horikoshii OT3. ACTA CRYSTALLOGR D, 2004, 60:577-579

[20] SHI N, LIU YW, NI MH et al. and RAO ZH. Expression, crystallization and preliminary X-ray studies of the recombinant PTB domain of mouse dok1 protein. ACTA CRYSTALLOGR D, 2004, 60:334-336

[21] CHANG L, ZHAO J, XU JX et al. and QI YF. Effects of taurine and homocysteine on calcium homeostasis and hydrogen peroxide and superoxide anions in rat myocardial mitochondria. CLIN EXP PHARMACOL P, 2004, 31:237-243

[22] HAN YG, HAN YG, LIU HL et al. and BI RC. Purification and refolding of human alpha 5-subunit (PSMA5) of the 20S proteasome, expressed as inclusion bodies in Escherichia coli. PROTEIN EXPRES PURIF, 2004, 35:360-365

[23] CHANG L, XU JX, ZHAO J et al. and QI YF. Taurine antagonized oxidative stress injury induced by homocysteine in rat vascular smooth muscle cells. ACTA PHARMACOL SIN, 2004, 25:341-346

[24] CAI N, HU KH, XIONG HT et al. and HU KH. Image segmentation of G bands of Triticum monococcum chromosomes based on the model-based neural network. PATTERN RECOGN LETT, 2004, 25:319-329

[25] LI FZ, HU KH, SU WF et al. and HU KH. Automatic recognition of small cell carcinoma based on the self-organizing neural network. BIO-MED MATER ENG, 2004, 14:175-184

[26] CAI N, HU KH, TAO W et al. and HU KH. Studies on the location of nucleolar DNA in situ in allium sativum cells and its structural model by image processing. PROG BIOCHEM BIOPHYS, 2004, 31:432-437

[27] LI ZJ, FANG W, XU JX et al. and XU JX. A Review on High Pressure Bioscience and Biotechnology. ACTA BIOPHYSICA SINICA, 2004, 20:1-6