个人情况

出生时间：1963年12月7日。
出生地点：广东汕头。
学位：大学本科，硕士，博士。
外语：熟练掌握英文和德文（读、听、写、说）
专业：微生物，发酵工程，分子生物学和药物中间体的合成。
职务：教授。

学位论文

1987-1989: 博士论文由Robert M. Lafferty教授指导
博士论文: Production of Poly(D-3-hydroxybutyrate-co-D-3-hydroxyvalerate) by pure and
mixed populations of strains of Alcaligenes latus DSM 1122, 1123 and 1124
奥地利格拉茨工业大学生物工程系。
1985-1987: 硕士论文由Robert M. Lafferty教授指导，奥地利格拉茨工业大学生物工程系。。
1981-1985: 学士论文《用相转移催化剂合成尼龙-6》由蔡刚教授指导，广州华南理工大学应用化学系。
1979-1981: 高中就读于汕头第十二中学。
1977-1979: 初中就读于汕头第十二中学中学部。

学术经历

1999-至今：清华大学博士生导师。
1997-至今：清华大学微生物教授。
1994-至今：清华大学教授本科生及硕士生《微生物》《现代微生物》《发酵技术》。
1994-至今：指导二十名博士生，二十九名硕士生及八十三名本科生论文。
1994-1997：清华大学微生物副教授，微生物学科带头人。
1992-1994：加拿大爱德蒙顿阿尔伯特大学生物系博士后。
1990-1992：英国诺丁汉大学药学系博士后。

主要论著目录

（近十年来论文发表情况）

一、SCI 论文（作为第一或通信作者）

1. Chen GQ, Koenig KH and Lafferty RM.Production of poly-D(-)-3-hydroxybutyrate and poly-D(-)-3-hydroxyvalerate by strains of Alcaligenes latus. Antonie van Leewenhoek 60 (1991) 61-66

2. Chen GQ, Koenig KH and Lafferty RM. Occurrence of poly-D(-)-3-hydroxyalkanoaies in the genus Bacillus. FEMS Microbiol. Letters 84 (1991) 173-176

3. Haigermoser C, Chen GQ, Grohman.E, Hrabak O and Schwab H. Stability of r-microbes: Stabilization of plasmid vectors by the partitioning function of broad-host-range plasmid RP4. J. Biotech 28 (1993) 219-299

4. Chen GQ, .Wu L, Coombes A, Davis SS and Illum L Preparation of human serum albumin microspheres by a novel acetone-heat denaturation method. J. Microencapsulation 11(1994) 395-407

5. Chen GQ and Page WJ The effect of substrate on the molecular weight of poly-beta-hydroxybutyrate produced by Azotobacter vinelandii UWD. Biotechnol. Lett 16 (1994) 155-160

6. Chen GQ and Page WJ. Production of poly-beta-hydroxybutyrate by Azotobacter vinelandii UWD in a two-stage fermentation process. Biotechnol. Techniques 11(1997) 347-350

7. Yu PH, Chua H, Huang AL. Lo W and Chen GQ. Conversion of Food industrial Wastes into Bio-plastics. Appl. Biochem. and Biotechnol. 70 (1998) 603-614

8. Kim TN, Feng QL, Kim JO,. Wu J, Wang H, Chen GQ and Cui FZ. Anti-microbial effects of metal ions (Ag+, Cu2+, Zn2+) in hydroxyapatite. J. Materials Science: Materials in Medicine 9 (1998) 129-134

9. He WN, Tian WD, Zhang G, Chen GQ and Zhang ZM. Production of novel polyhydroxyalkanoates by Pseudomonas stutzeri 1317 from glucose and soybean oil. FEMS Microbiol. Lett. 169 (1998) 45-49

10. Hong K, Sun SQ, Tian WD and Chen GQ. A rapid method for detecting bacterial PHA in intact cells by FT-IR. Appl. Microbiol. Biotechnol. 51 (1999) 523-526

11. Yao J, Zhang G, Wu Q, Chen GQ and Zhang RQ. Production of polyhydroxyalkanoates by Pseudomonas nitroreducens. Antonie van Leewenhoek 75 (1999) 345-349

12. Microbial synthesis and characterization of polyhydroxyalkanoates by strain DG17 from glucose. He WN, Zhang ZM, Hu P and Chen GQ. Acta Polymerica Sinica 6 (1999) 709-714

13. Zhang DM, Cui FZ, Luo ZS, Lin YB, Zhao K and Chen GQ. Wettability improvement of bacterial polyhydroxyalkanoates via ion implantation.. Surface & Coating Technology 131 (2000) 1-5

14. Xi JZ, Wu Q, Yan YB, Zhang ZM, Yu HP, MK Cheung, Zhang RQ and Chen GQ. Hyperproduction of polyesters consisting of medium-chain-length hydroxyalkanoate monomers by strain Pseudomonas stutzeri 1317. Antonie van Leeuwenhoek 78 (2000): 43-49

15. Hong K, Chen GQ, PH Yu, Zhang G and Liu Y. Effect of C/N ratio on monomer composition of polyhydroxyalkanoate (PHA) produced by Pseudomonas mendocina 0806 and Pseudomonas pseudoalkaligenus YS1, Appl. Biochem. and Biotechnol. 84-86 (2000): 971-980

16.. Feng QL, Wu J, Chen GQ, Cui FZ, Kim TN, Kim JO. A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. J Biomed Mater Res 52 (4) (2000) 662-8

17. Sun SQ, Zhou Q, Hou WJ, Wu Q, Chen GQ. Study on mechanism of different PHAs during heating by FTIR. Spectroscopy and Spectral Analysis 20 (5) (2000) 677-678

18. Tian WD, Hong K, Chen GQ, Wu Q, Zhang RQ and Huang WY. Production of polyesters consisting of medium chain length 3-hydroalkanoic acids by Pseudomonas mendocina 0806 from various carbon sources. Antonie van Leewenhoek 77 (2000) 31-36

19. Chen GQ, Wu Q, Zhao K, Yu HP & Chan A. Chiral Biopolyesters-Polyhydroxyalkanoates Synthesized by Microorganisms. Chinese J of Polymer Science 18 (2000) 389-396

20. Wu Q, Sun SQ, Yu PHF, Chen AXZ, Chen GQ. Environmental Dependence of Microbial Synthesis of Polyhydroxyalkanoates. Acta Polymerica Sinica 6 (2000) 751-756

21. Chen GQ, Xu J, Wu Q, Zhang ZM and Ho KP. Synthesis of copolyesters consisting of medium-chain-length polyhydroxyalkanoates by Pseudomonas stutzeri 1317. Reactive & Functional Polymers 48 (2001) 107-112

22. Tian G, Wu Q, Sun SQ, Noda I,Chen GQ. Study of Thermal Melting Behavior of Microbial Polyhydroxyalkanoates Using Two-Dimensional Fourier-Transform Infrared FT-IR Correlation Spectroscopy. Appl. Spectroscopy 55(7) (2001) 888-894

23. Wu Q, Tian G, Wu Q, Sun SQ, Noda I, Chen GQ Study of Microbial Poly(hydroxybutyrate-co-hydroxyhexanoate) Using Two-Dimensional Fourier-Transform Infrared Correlation Spectroscopy. J Appl Polym Sci. 82 934-940 (2001)

24 Wu Q, Huang HH, Hu GH, Chen JC, Ho KP, Chen GQ. Constitutive Production of Poly-3-hydroxybutyrate by strain of Bacillus aureus JMa5 Cultivated in Molasses Media. Antonie van Leeuwenhoek 80 (2) (2001)111-118

25. Zhang G, Hang XM, Green P, Ho KP, Chen GQ. PCR Cloning of Type II Polyhydroxyalkanoate Biosynthesis Genes from two Pseudomonads strains. FEMS Microbiology Lett 198 (2) (2001) 165-170

26. Chen GQ, G. Zhang, S. J. Park, S. Y. Lee: Industrial Production of Poly(hydroxybutyrate-co-hydroxyhexanoate). Appl Microbiol Biotechnol 57 (2001) 57: 50-55

27. He JD, Cheung MK, Yu PHF, Chen GQ. Thermal Analyses of Poly(3-hydroxybutyrate), Poly(3-hydroxy-butyrate-co-hydroxylvalerate) and Poly(3-hydroxybutyrate-co-hydroxyl -hexanoate). J. Appl. Polym. Sci. 82 (1) (2001) 90-98

28. Zhao K, Yang XS, Chen JC, Chen GQ. Effect of Lipaase Treatment on the Biocompatibility of Microbial Polyhydroxyalkanoates. J Mater Sci. Mater in Med 13 (2002): 849-854

29. Tian G, Wu Q, Sun SQ, Noda I, Chen GQ. Two-Dimensional Fourier-Transform Infrared Spectroscopy Study of Biosynthesized Poly(hydroxybutyrate-co-hydroxyhexanoate) and Poly(hydroxybutyrate-co-hydroxyvalerate). J of Polymer Sci. Part B 40 (7) (2002) 649-656

30. Hang XM, Zhang G, Wang GL, Zhao XH, Chen GQ. PCR cloning of polyhydroxyalkanoate biosynthesis genes from Burkholderia caryophylli and their functional expression in recombinant Escherichia coli. FEMS Microbiol Lett 210 (2002) 49-54

31. Yang XS, Zhao K, Chen GQ. Effect of Surface Treatment on the Biocompatibility of Microbial Polyhydroxyalkanoates. Biomaterials 23 (5) (2002) 1391-1397

32. Qu J, Chen W, Luo G, Wang YM, Xiao SY, Ling Z, Chen GQ. Rapid determination of underivatized pyroglutamic acid, glutamic acid, glutamine and other relevant amino acids in fermentation media by LC-MS-MS. Analyst. 127 (1) (2002) 66-69

33. Xu J, He WN, Guo BH, Hu P, Zhang ZM, Zhang G, Lin HL, Chen JC, Chen GQ. A mathematical model for biosynthesis of medium-chain-length polyhydroxyalkanoates by Pseudomonas stutzeri 1317. Chemical J Chinese Universities. 23 (1) (2002) 71-74

34. Deng Y, Zhao K, Zhang XF, Hu P, Chen GQ. Study on the three-dimensional proliferation of rabbit articular cartilage derived chondrocytes on polyhydroxyalkanoate scaffolds. Biomaterials 23 (20) (2002) 4049-4056.

35. Hang XM, Lin ZX, Chen GQ. Polyhydroxyalkanoate Biosynthesis by Pseudomonas pseudoalcaligenes YS1. FEMS Microbiol Lett 212 (1) (2002) 71-75

36. Chen GQ. Production and Applications of Microbial Polyhydroxyalkanoates. Macromolecular Symposia (in press)

37. Gao HJ, Wu Q, Chen GQ. A Novel Genetically Engineered Pathway for Production of D-(-)-3-hydroxybutyric acid by recombinant Escherichia coli. FEMS Microbiol Lett 213 (2002) 59-65

38 Xu J, Guo BH, Zhang ZM, Chen GQ and Wang XF. Topography of polyhydroxybutyrate banded spherulites. Chem J Chinese Univ. 23 (2002)1216-1218

39. Zhou Q, Zhang L, Fu XQ, Chen GQ. Quantitation of Yeast Ceramides Using High-Performance Liquid Chromatography Equipped with Evaporative Light-Scattering Detector. J Chromatogr B Analyt Technol Biomed Life Sci 780 (1) (2002):161-168

40. Zhao K, Deng Y, Chen CJ, Chen GQ. Polyhydroxyalkanoate (PHA) Scaffolds with Good Mechanical Properties and Biocompatibility. Biomaterials. 24 (6) (2003) 1041-1054

41. Zhao K, Deng Y, Chen GQ. Effects of Surface Morphology on the Biocompatibility of Polyhydroxyalkanoates. Biochemical Eng J (in print)

42. Tian G, Wu Q, Sun SQ, Noda I, Chen GQ. Study of Pre-melting and Crystallization Process of Biosynthesized Poly(3-hydroxybutyrate) Using Two-dimensional Fourier-Transform Infrared Spectroscopy. Chem J Chinese Universities 8 (2002) 1627-1631

43. Zhao K, Tian G, Zheng Z, Chen JC, Chen GQ. Effect of acrylic acid on Production of D-(-)-3-hydroxybutyric acid and D-(-)-3-hydroxyalkanoic acid by recombinant Escherichia coli. FEMS Microbiol Lett 218 (2003) 59-64

44. Xu J, Guo BH, Yang R, Wu Q, Chen GQ, Zhang ZM. In situ FTIR study on melting and crystallization of polyhydroxyalkanoates. Polymers 43 (25) (2002) 6893-6899

45. Zheng Z, Deng Y, Lin XS, Zhang LX, Chen GQ. Induced Production of Rabbit Articular Cartilage-Derived Chondrocytes Collagen II on Polyhydroxyalkanoates Blend. J Biomater Sci. Polymer Edition (accepted in 2003)

46. Lu XY, Wu Q, Chen GQ. Enhanced production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) via manipulating the fatty acid oxidation pathway in E. coli. FEMS Microbiol Lett 221 (2003) 97-101

47. Zhang ML, Xie JP, Zhou Q,Chen GQ and Liu Z. On-line solid-phase extraction of ceramides from yeast with ceramide III imprinted monolith. J Chromatography A. 984 (2) (2003) 173-183

48. Wu Q, Zheng Z, Xi JZ, Gao HJ and Chen GQ. Production of 3-(R)-Hydroxybutyric acid by Recombinant Escherichia coli HB101 Harboring Genes of phbA and phbB. Chem Eng J Japan (accepted in 2003)

49. Deng Y, Lin XS, Zheng Z, Deng JG, Chen JC, Ma H, Chen GQ. Poly(hydroxybutyrate-co-hydroxyhexanoate) Promoted Production of Extracellular Matrix of Articular Cartilage Chondrocytes in vitro. Biomaterials 24 (2003) 4273-4281

50. Wang YW, Chen GQ, Wu Q. Increased Hydrophilicity of Microbial Polyhydroxyalkanoates via Hyaluronan Coating Reduced Growth of Mouse Fibroblast L929 Cells. Biomaterials (in press)

51. Ye B, Cui K, Feng QL, Chen GQ, Cui FZ Synthesis and high temperature resistance properties of silver loaded fluorapatite antibacterial. J Inorg Mater 18 (2)(2003) 485-489

52. Zheng Z, Zhang MJ, Zhang G and Chen GQ. Production of 3-hydroxydecanoic acid by recombinant Escherichia coli HB101 barboring phaG gene. Antonie van Leeuwenhoek (accepted in 2003)

53. Wang YW, Wu Q and Chen GQ. Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) Scaffolds with Good Biocompatibility for Osteoblast Proliferation and Differentiation. Biomaterials (accepted in 2003)

54. Lu XY, Wu Q and Chen GQ. Production of Poly(3-hydroxybutyrate-co-3- hydroxyhexanoate) with Flexible 3-hydroxyhexanoate Content in Aeromonas hydrophila CGMCC 0911. Appl Microbiol Biotechnol (accepted in 2003)

55. Qiu YZ, Ouyang SP, Liu LP, Wu Q, Chen GQ. Production of Copolyesters Consisting of 3-Hydroxybutyrate and 3-Hydroxyhexanoate by Recombinant Aeromonas hydrophila Harboring phbA and phbB Genes. Appl Environ Microbiol (submitted in 2003)

56. Feng LD, Watanabe T, He Y, Wang Y, Kichise T, Fukuchi T, Chen GQ, Doi Y and Inoue Y. Phase behavior and Thermal Properties for Binary Blends of Bacterial Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)s with Narrow-Comonomer-Unit Compositional Distribution. Macromolecular Biosci. 3 (2003) 310-319

57. Xu J, Guo BH, Chen GQ, Zhang ZM New growth features of poly(3-hydroxybutyrate-co-3- hydroxylhexanoate) banded spherulites. Polymer J. 35 (2003): 460-464

58. Zheng Z, Gong Q and Chen GQ. Synthesis of 3-Hydroxydecanoic Acid from Recombinant Pseudomonas putida Harboring Thioesterase II Encoding tesB Gene. FEMS Microbiol Lett (submitted in 2003)

59. Wang YW, Wu Q and Chen GQ. Evaluation of Poly (3-hydroxybutyrate-co-3-hydroxyl- hexanoate) for Biomedical Application: Surface Characteristics, Protein Adsorption and in Vitro Degradation. Biomaterials (submitted in 2003)

参与专业书籍的编写

1.《工业微生物基础及其应用》。徐浩等。科学出版社（1991）

2. 跨世纪的高分子科学：微生物法合成高分子材料。胡汉杰等。化学工业出版社（2001）

3.《生物高聚物》(陈国强等) (化学工业出版社) (进行中)

4.《用生物学的方法合成聚合体》(化学工业出版社)(进行中)