王瑛 进化遗传学和比较功能基因组学实验室负责人
姓名 王瑛
性别 女
职称 研究员
学历 博士
电话 027-87510675
传真 027-87510331
电子邮件 yingwang@wbgcas.cn
通讯地址 湖北武汉磨山中科院武汉植物园
邮政编码 430074
研究领域
My research in Wuhan Botanical Garden will focus on evolutionary genomics and comparative functional genomics of Solanaceous and Berberidaceous species. For the Solanaceous species, genome duplication, especially the large fragment duplication, will be studied based on the known EST and genomic sequences and marker information from SGN (www.sgn.cornell.edu). Tomato paralogs and corresponding orthologs will be computationally identified and confirmed in the wet lab through mapping and sequencing. Gene expression and function of paralogs and orthologs will be studied through Northern, RT-PCR, and gene transformation. The Epimedium genus in Berberidaceae has about 57 identified species, with 47 species known as YinYangHuo and widely distributed in China. Although Epimedium species are traditional Chinese medicinal plants used for hypogonadism, spermatorrhea, improvement of immune function etc., little is known about these plant species, especially at the molecular level. The genetics studies are proposed for Epimediums, including molecular systematics of Epimedium species, natural genetic diversity evaluation of major species used for medicinal purpose, heredity of biosynthesis of phytochemicals, conservation of Epimediums, cultivar selection from wild species and molecular breeding. cDNA libraries will be constructed using young and mature leaves, flower, and roots tissues. EST sequences will be analyzed for genome characterization, gene expression profile, and identification of genes related to secondary metabolism. Ortholgous genes related to biosynthesis of phytochemicals will be explored in the close related Mahonia and Berberis species, that are also traditional Chinese medicinal plants, and compared with other model species. Bioinformatics component (e.g. databases, websites, and sequence analysis) will be developed for storing, management, and analysis of sequences, annotation results, and natural diversity.
获奖及荣誉
2004 入选中科院” 百人计划”
1999 – 2001 Wade Stackhouse Fellowship, Clemson University
2000 Schilletter Fellowship, Clemson University
2000 Student travel award in ASHS (American Society of Horticultural Science)
conference 代表论著
Wang Y., J. Giovannoni, R. Wing, S. Tanksley 2005 Comparative genomics of Solanaceous species. In preparation for PNAS
Wang Y., R. Van der Hoeven, R. Nielsen, L. Mueller, S. Tanksley. 2005 Characteristics of the tomato nuclear genome as determined by sequencing unmethylated DNA. Submitted to Plant Physiology
Wang Y., G. L. Reighard, D. R. Layne, A. G. Abbott, H. Huang. 2005 Inheritance of AFLP markers and their use for genetic diversity analysis in wild and domesticated pawpaw (Asimina triloba). In press by JASHS
Wang Y., G. L. Reighard, R. Scorza, and A. G. Abbott. 2002. Genetic mapping of the evergrowing gene locus in peach [Prunus persica (L.) Batsch] genome. J. of Heredity 93:352-358.
Wang Y., L.L. Georgi, T. N. Zhebentyayeva, G. L. Reighard, R. Scorza, and A. G. Abbott. 2002. High throughput targeted SSR marker development in peach [Prunus persica (L.) Batsch]. Genome 45:319-328.
Wang Y., L. Garay, L. L. Georgi, G. L. Reighard, R. Scorza, and A. G. Abbott. 2002. Development of Bacterial Artificial Chromosome Contigs in the evergrowing Gene Region in Peach [Prunus persica (L.) Batsch]. Acta Hort. (ISHS) 592:183-189.
Huang H., Y. Wang, Z. Zhang, Z. Jiang and S. Wang. 2004. Actindia germplasm resources and kiwifruit industry in China. HortScience 39 (6):1165-1172
Xu Y., Z. Li, Y. Wang, H. Huang. 2004 Status and prospect of studies on Epimedium species, the traditional Chinese herbal plants. Chinese Medicinal Plants. 36(2): 289-295 (in Chinese with English abstract)
李作洲，徐艳琴，王瑛，黄宏文. 2005. 淫羊藿属药用植物的研究现状与展望. 中草药，36(2): 289 ~ 295.
Bielenberg, D. G., Y. Wang, S. Fan, G. L. Reighard, R. Scorza, and A. G. Abbott. 2004 A Deletion Affecting Several Gene Candidates is Present in the Evergrowing Peach Mutant. Journal of Heredity 95(4):441–449
Zhen Y., Z. Li, H. Huang and Y. Wang. 2004. Molecular characterization of kiwifruit (Actinidia) cultivars and selections using SSR markers. J. Amer. Sco. Hort. Sci. 129(3):374-382
Li Z., J. Gong, Y. Wang and H. Huang. 2003. Spatial structure of AFLP genetic diversity of remnant populations of Metasequoia glyptostroboides (Taxodiaceae). Biodiversity Scieces 11 (4): 265-275 (in Chinese with English abstract)
Georgi L. L., Y. Wang, and A. G. Abbott. 2003. Comparison of Peach and Arabidopsis sequences: a mosaic of colinear fragments. Genome 46:268-276.
Georgi L. L., Y. Wang, and A. G. Abbott. 2002. Construction of a BAC library and its application to the identification of simple sequence repeats. Theoretical and Applied Genetics. 105:1151-1158.
Salava J., Wang Y., Krska B., Polak J., Komonek P., Miller W., Dowler W., Reighard G.L., Abbott A.G. (2002). Identification of molecular markers linked to resistance of apricot (prunus armeniaca L.) to plum pox virus. Journal of Plant Disease and Protection, V. 109 (1), 64-67.
Abbott A. G., L.L. Georgi, Y. Wang, D. 2002. Yuergmiaux, M. Inigo, B. Sosinski, A. Blenda, and G. Reighard. Peach: the model genome for Rosaceae. Acta Hort. (ISHS) 592:199-209.
承担科研项目情况
主持以下课题:
武汉晨光计划: 茄子和番茄中数量性状基因的比较功能基因组学研究
武汉植物园创新课题: 淫羊霍属药用植物的遗传学、基因组学、和比较基因组学研究
国际合作课题: 淫羊霍的分子育种
参与以下课题:
国际合作课题: 番茄的全基因组测序和茄科植物的比较基因组学研究
自然科学基金项目: 天麻共生体的遗传多样性和协同进化的分子遗传机理的研究
