
李中军 教授 博士生导师(药物化学)
1987.7毕业于北京医科大学药学院化学专业;1992.7获得北京医科大学药学院药物化学专业理学博士;1992.8~ 现在 ,北京大学药学院化学生物学系(原北京医科大学药学院生物有机化学系),讲师、副教授、教授。从事与有机化学、有机合成化学、糖化学和化学糖生物学相关的教学和科研。
研究领域:
1.天然产物及其类似物的合成;
2.糖化学及化学糖生物学:寡糖合成新方法、新策略,生物活性糖类化合物(寡糖、糖肽、缀合物)设计、合成及与生物大分子的相互作用,糖类药物及其SAR研究;
3.血吸虫病合成多肽疫苗的研究;
4.新药研究与开发。
电话:010-62091504,62091714
传真:010-62367134
电子信箱:zjli@bjmu.edu.cn
代表性的文章:
1. Zhi-Hui Qin, Hui Li, Meng-Shen Cai, Zhong-Jun Li, Bromonium Ion Promoted Glycosidic Bond Formation and its Simultaneous Bromination Effect of the Activated Aromatic Ring, Carbohydr. Res., 2002, 337:31-36.
2. Bin SU, Hui LI, Meng Shen CAI, Zhong Jun LI, On the mechanism of condensation between 5-Amino-4, 6-dichloro-2-methylpyrimidine and 1-acetyl-2- imidazolin-2-one, Chin. Chem. Lett., 2002, 13(3):207~210.
3. Zhi-Hui Qin, Hui Li, Hong Liu, Meng-Shen Cai, Zhong-Jun Li, Syntheisi of a Potential Tetrasaccharide Ligend for E-Selectin, Carbohydr. Res., 2002, 337:621-628.
4. Zhong-Jun Li, Hui Li, Yi-Ping Lu, Xu-Ling Shi and Meng-Shen Cai, An Abnormal Deallylation Reaction of an L-Fucopyrano-side, Carbohydr. Res., 1999, 317:191-192.
5. Xiang-Bao Meng, Lian-Dai Yang, Hui Li, Qing Li, Tie-Ming Cheng, Meng-Shen Cai, Zhong-Jun Li, Facile Synthesis of Carbohydrate-centered 1-Thio-b-D-lactoside Clusters with Potential Anti-metastatic Activity, Carbohydr. Res., 2002, 337:977..
6. Yi-Ping Lu, Hui Li, Meng-Shen Cai, Zhong-Jun Li, Synthesis of a divalent glycoside of an a-galactosyl disaccharide epitope involved in the hyperacute rejection of xenotransplantation, Carbohydr. Res., 2001, 334:289.
7. Hui Li, Qing Li, Meng-Shen Cai, Zhong-Jun Li, Synthesis of galactosyl and lactosyl derivatives as potential anti-metastasis compounds, Carbohydr. Res., 2000, 328:611.
8. San-Qi Zhang, Zhong-Jun Li, An-Bang Wang, Meng-Shen Cai, Synthesis of a Phenylpropanoid Glycoside, Osmanthuside B6, Carbohydr Res., 1998, 308:281.
9. Qing Li, Hui Li, Meng-Shen Cai, Zhong-Jun Li and Rou-Li Zhou, Studies on Carbohydrates XXXIII. Synthesis of Spacer Armed 2-Acetamido-2-deoxy-4-O-b-D-galactopyranosyl-a-D-mannosides and Their Dimers, Tetrahedron (Asymmetry) , 1999, 10:2675
10. Zhong-Jun Li, Hui Li and Meng-Shen Cai, Synthesis of a Tetrasaccharide Fragment of Cobra Venom Factor Oligosaccharide, Carbohydr. Res., 1999, 320:1.