罗永章 博士 清华大学肿瘤生物学实验室主任

联系方式:
电话：+86-10-62772897 传真：+86-10-62794691
E-mail:protein@tsinghua.edu.cn Web: http://www.luolab.org

教授，博导，长江学者特聘教授，国家杰出青年基金获得者

1985年，兰州大学化学系物理化学专业 学士
1989年，美国田纳西州大学诺克斯维尔分校生物化学系生物化学专业 硕士
1993年，美国加州大学伯克利分校分子与细胞生物学系生物化学专业 博士
现任清华大学教授

主要科研领域与方向：
1. 新生血管生成和调控的分子机理以及信号转导途径
2. 蛋白质折叠与分子伴侣
3. 蛋白质错误折叠与折叠病

Selected Publications
■ Yujie Huang, Nan Song, Yanping Ding, Shaopeng Yuan, Xuhui Li, Hongchen Cai, Hubing Shi, Yongzhang Luo (2009). "Pulmonary vascular destabilization in the pre-metastatic phase facilitates lung metastasis" Cancer Research (Accepted)
■ Shaopeng Yuan, Yan Fu, Xiaofeng Wang, Hubing Shi, Yujie Huang, Xiaomin Song, Ling Li, Nan Song, & Yongzhang Luo (2008). "Voltage dependent anion channel 1 is involved in endostatin-induced endothelial cell apoptosis" The FASEB Journal 22, 2809-2820.
■ Yan Fu, Xiaoyu Wu, Qing Han, Yun Liang, Yingbo He, & Yongzhang Luo (2008). "Sulfate stabilizes the folding intermediate more than the native structure of endostatin" Archives of Biochemistry and Biophysics, 471, 232-239.
■ Hubing Shi, Yujie Huang, Hao Zhou, Xiaomin Song, Shaopeng Yuan, Yan Fu, & Yongzhang Luo (2007). "Nucleolin is a Receptor that Mediates Antiangiogenic and Anti-tumor Activity of Endostatin", Blood (Cover Story) 110, 2899-2906
Comment on Shi et al, page 2899
Judah Folkman (2007). "Endostatin finds a new partner: nucleolin" Blood 110, 2786-2787
■ Qing Han, Yan Fu, Hao Zhou, Yingbo He, & Yongzhang Luo (2007). "Contributions of Zn(II)-Binding to the structural stability of endostatin" FEBS Letters 581, 3027-3032
■ Yunzhou Wei, Hao Zhou, Yi Sun, Yingbo He, & Yongzhang Luo (2007). "Insight Into the Catalytic Mechanism of Arginine Deiminase: Functional Dtudies on the Crucial Sites" PROTEINS: Structure, Function, and Bioinformatics 66, 740-750.
■ Yujie Huang, Hubing Shi, Hao Zhou, Xiaomin Song, Shaopeng Yuan, & Yongzhang Luo (2006). "The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin" Blood 107, 3564-3571.
■ Yingbo He, Hao Zhou, Huadong Tang, & Yongzhang Luo (2006). "Deficiency of Disulfide Bonds Facilitating Fibrillogenesis of Endostatin" J. Biol. Chem. 281, 1048-1057.