盛国庆 博士 中国科学院广州生物医药与健康研究院研究员

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盛国庆 博士 中国科学院广州生物医药与健康研究院研究员

联系方式:sheng_guoqing@gibh.ac.cn

研究兴趣
能量平衡、应激和糖稳定的中枢调节.
神经发育和神经系统疾病
干细胞和和神经生成
药物靶点确立和新药评价

教育
2000-2003 北京大学博士, 药理学
1997-2000 徐州医学院硕士,药理学
1992-1997 徐州医学院医学系,临床医学

专业工作经验
2003-2007 美国Emory大学医学院 博士后
1996-1997 徐州市第一医院, 实习医生

论文发表选录
1. Sheng G.Q., Chang G.Q., Lin J.Y., Yu Z.X., Fang Z.H., Rong J., Lipton S.A., Li S.H., Leibowitz S., Li X.J. Hypothalamic Huntingtin Associated Protein-1 As a Mediator of Feeding Behavior. Nat Med, 2006, 12(5): 526-533

2. Rong J., McGuire J., Fang Z., Sheng G.Q., Shin J.Y., Li S.H., Li X.J. Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth. Journal of Neuroscience, 2006, 26: 6019-6030

3. Rong J., Li S., Sheng G.Q., Wu M., Coblitz B., Li M., Fu H., Li X.J. 14-3-3 protein interacts with huntinting-associated protein 1 and regulates its trafficking. Journal of Biological Chemistry, 2006, 282:4748-4756

4. Ringrose A., Zhou Y., Pang E., Zhou L., Lin A., Sheng G., Li X.J., Andrew Weng, Su M., Pittelkow M.R., and Jiang X. Evidence for an Oncogenic Role of AHI-1 in Sezary Syndrome, a Leukemic Variant of Human Cutaneous T-cell Lymphomas. Leukemia, 2006, 20(9): 1593-1601

5. Sheng G.Q., Pu X.P., Lei L., Tu P.F., Li C.L. Tubuloside B from Cistanche salsa rescues the PC12 neuronal cells from 1-methyl-4-phenylpyridinium ion induced apoptosis and oxidative stress. Planta Medical, 2002, 68(11): 966-70

6. Sheng G.Q., Zhang J.R., Pu X.P., Ma J., Li C.L. Protective effect of verbascoside on 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells. Eur J Pharmacol, 2002,451(2): 119-124

7. Zhang J.R., Lin C.Z., Yang X.X., Lu K.R. Sheng G.Q., Dai T.J. Effect of propofol on plasma membrane fluidity in PC12 cells and liposome. Chinese Journal of Clinical pharmacology Therapy, 2003, 8(2) 129-132

8. Sheng G.Q., Zhang J.R., Xing S.H., Pu X.P., Li C.L., Dai T.J. Effects of ketamine on precipitated morphine withdrawal symptoms in rats and its possible mechanism. Chinese Journal of Pharmacology and Toxicology, 2002,16(2): 88-92

9. Sheng G.Q., Zhang J.R., Dai T.J., Pu X.P., Li C.L. Effect of propofol on membrane fluidity and intracellular free Ca2 + concentration in PC12 cells. Chinese Pharmacological Bulletin, 2002,18(3): 264-266

10. Sheng G.Q., Pu X.P., Li C.L. The progress in the proteomics researches of central nervous system diseases and drugs. Chinese Pharmacological Bulletin, 2001,17(5): 481-484

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