
王伟博士 湖北省神经系统疾病重点实验室
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近五年主持的部分国家科研项目: 国家自然科学基金重点项目(30230140),胶质细胞细胞周期调控及其结构和功能关系的研究,2003-2006,160万元 国家科技部973重大专项项目(2006CB504502),经穴效应特异性及影响因素研究,2006-2010,200万元 国家自然科学基金(30170332),细胞周期调控与缺血脑区胶质细胞增殖关系的研究,2002-2004,18万元 卫生部重点装备基金,急性脑梗塞缺血半暗带临床界定及有效治疗,2001-2004,166万元
获奖: 脑-脑脊液免疫神经内分泌回路与癫痫发病机理的关系,中华医学科技奖二等奖,2002年 脑-脑脊液免疫神经内分泌回路与癫痫发病机理的关系,中国高校自然科学奖二等奖,2000年
代表性研究论文: 1 Wang W (王伟), Redecker C, Bidmon HJ, Witte OW. Delayed neuronal death and damage of GDNF family receptors in CA1 following focal cerebral ischemia. Brain Res, 1023 92–101, 2004. (IF:2.474) 2 Redecker C, Wang W (王伟), Fritschy JM, Witte OW. Widespread and long-lasting alterations in GABAa-receptor subtypes after focal cortical infarcts in rats: mediation by NMDA-dependent processes. J Cereb Blood Flow Metab, 22:1463-1475,2002. (IF:5.370) 3 Zhijun Zhang, Gang Chen, Wei Zhou, Aihong Song, Tao Xu, Qing-ming Luo, W Wang (王伟), Xiao-song Gu , Shumin Duan. Regulated ATP release from astrocytes via lysosome exocytosis. Nature Cell Biology (In press, 参与作者, IF:20.649) 4 Zhu Z, Zhang Q, Yu Z, Zhang L, Tian D, Zhu S, Bu B, Xie M, Wang W (王伟),. Inhibiting cell cycle progression reduces reactive astrogliosis initiated by scratch injury in vitro and by cerebral ischemia in vivo. Glia. 2007, 55(5): 546-558.(IF=4.8,封面文章, 通讯作者) 5 Dai-Shi Tian, Zhi-Yuan Yu, Min-Jie Xie, Bi-Tao Bu, Otto W. Witte, WWang (王伟),.. Suppression of astroglial scar Formation and enhanced axonal regeneration associated withfunctional recovery in a spinal cord injury rat model by the cell cycle inhibitor olomoucine. Journal of Neuroscience Research 2006, 84:1053-1063. (IF:3.8, 通讯作者) 6 Li Ni, Jiagao Lü, Ling Bo Hou, Jiang Tao Yan, Qiao Fan,Rutai Hui,Katherine Cianflone, W Wang (王伟), Dao Wen Wang. Cystatin C, Associated with Hemorrhagic and Ischemic Stroke, Is a Strong Predictor of the Risk of Cardiovascular Eventsand Death in Chinese - Graeme Hankey. Stroke,2007 (IF=5.855, In press, 共同通讯作者) |