
中青年骨干:陈绪林博士,研究员、博导
学习简历
1983-1987 四川大学 微生物学专业 学士学位
1987-1990 武汉大学 分子病毒学专业 硕士学位
1996-1999 中国科学院微生物学研究所 微生物学专业 博士学位
工作简历
8/2004 – 现在 中科院武汉病毒抗病毒药物学科组所 研究员
4/2003 – 7/2005 Fox Chase 癌症中心人类遗传学研究小组 研究助理
10/1999-3/2003 宾夕法尼亚大学牙科医学院, 微生物系 博士后
9/1990-8/1996 大连医科大学微生物及免疫学教研室 讲师
代表性学术论文:
1: Chen X, Wang L, Fazlieva R, Kruger WD. Contrasting behaviors of mutant cystathionine beta-synthase enzymes associated with pyridoxine response. Hum Mutat. 2006 May;27(5):474-82.
2: Dorjsuren D, Burnette A, Gray GN, Chen X, Zhu W, Roberts PE, Currens MJ, Shoemaker RH, Ricciardi RP, Sei S. Chemical library screen for novel inhibitors of Kaposi's sarcoma-associated herpesvirus processive DNA synthesis. Antiviral Res. 2006 Jan;69(1):9-23.
3: Wang L, Chen X, Tang B, Hua X, Klein-Szanto A, Kruger WD. Expression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model. Hum Mol Genet. 2005 Aug 1;14(15):2201-8.
4: Chen X, Jhee KH, Kruger WD. Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine. J Biol Chem. 2004 Dec 10;279(50):52082-6.
5: Chen X, Lin K, Ricciardi RP. Human Kaposi's sarcoma herpesvirus processivity factor-8 functions as a dimer in DNA synthesis. J Biol Chem. 2004 Jul 2;279(27):28375-86.
6: Ricciardi RP, Lin K, Chen X, Dorjsuren D, Shoemaker R, Sei S. Rapid screening of chemical inhibitors that block processive DNA synthesis of herpesviruses: potential application to high-throughput screening. Methods Mol Biol. 2005;292:481-92.