Reproductive and Developmental Biology of Kunming Primate Research Center
Principal Investigator: Professor Weizhi JI
Professor Weizhi JI， Director of Kunming Primate Research center, the Chinese Academy of Sciences, and director of Yunnan Key Laboratory for Animal Reproductive Biology, is engaged in researching on primate biology. His research interests cover many areas in reproductive and developmental biology. In recent years, the major studies focus on the regulation of oocytes maturation, development and differentiation of early embryos as well as somatic cell nuclear techniques; cryopreservation of germ cells (oocyte, sperm, and embryo), non-human primate cloning and establishment and directing differentiation of primate embryonic stem cells.
Selected Publications:
Li YH, Cai KJ, Li J, Dinnyes A, Ji W 2006 Comperative studies with six extenders for sperm cryopreservation in the cynomolgus monkey(Macacca fascicularis) and rhesus monkey (Macaca mulatta). Am. J. Primatol. 68: 39-49.
Li Tianqing, Zheng Jiawei, Xie Yunhua, Wang Shufen, Zhang Xiuzhen, Li Jian, Jin Lifang, Ma Yuanye, Wolf Don P., Zhou Qi, Jia Weizhi. Transplantable Neural Progenitor Populations Derived from Rhesus Monkey Embryonic Stem Cells. Stem Cells. 2005. 23: 1295 – 1303.
Li Tianqing, Wang Shufen, Xie Yunhua, Lu Yongqing, Zhang Xiuzhen, Wang Liu, Yang Shihua, Wolf Don, Zhou Qi, Ji Weizhi.Homologous Feeder Cells Support Undifferentiated Growth and Pluripotency in Monkey Embryonic Stem Cells.Stem Cells. 2005; 23: 1192 – 1199.
Zheng P, Si W, Bavister BD, Yang JF, Ding CH, Ji WZ 2003 17-b estradiol and progesterone improve in vitrocytoplasmic maturation of oocytes from unstimulated prepubertal and adult rhesus monkeys. Human Reproduction 18: 2137-2144.
Ma L, Tai H, Li C, Zhang Y, Wang ZH, Ji WZ 2003 Photodynamic inhibitory effects of three perylenequinones on human colorectal carcinoma cell line and primate embryonic stem cell line. World Journal of Gastroenterology 9: 485-490.
Ma J, Zhou HL, Su L, Ji WZ 2002 Effects of exogenous double-stranded RNA on the basonuclin gene expression in mouse oocytes. Science in <
Zheng P, Wang H, Bavister BD, Ji WZ. 2001 Maturation of rhesus monkey oocytes in chemically defined culture media and their functional assessment by in vitro fertilization and embryo development. Human Reprod. 16: 300-305
Si W, Tang XH, He XC, Zheng P, Bavister BD, Ji WZ, 2000 Cryopreservation of rhesus monkey (Macaca mulatta) spermatozoa and their functional assessment by in vitro fertilization. Cryobiology 41: 232-240.
